Born in Columbus, Ohio in 1981, Sai Varadan spent his early childhood in Pennsylvania before moving to Brooklyn as a teenager. He attended the Pratt Institute High School Program for Gifted Artists, and later enrolled at the School of Visual Arts where he studied animation. He received his B.A. in film and television from NYU's Tisch School of the Arts and also double-majored in sociology. He completed his thesis film God's Hand in late 2004. His future plans include writing/directing feature films, writing and drawing his own comic book, and running V-TWINZ Productions Inc. with his twin brother Venk.